Skip to main content

"The Krebs Cycle: A Crucial Metabolic Pathway for Energy Production and Amino Acid Synthesis in Cells"

 The Krebs cycle (also known as the citric acid cycle or tricarboxylic acid cycle) is a crucial metabolic pathway that occurs in the mitochondria of cells. It's a key process by which cells generate energy from the food they consume.


Key Steps of the Krebs Cycle:




1. *Citrate formation*: Citrate is formed from acetyl-CoA and oxaloacetate.

2. *Citrate conversion*: Citrate is converted into isocitrate through an isomerization reaction.

3. *Decarboxylation*: Isocitrate undergoes decarboxylation to form α-keto glutarate.

4. *Oxidation*: α-Keto glutarate is oxidized to form succinyl-CoA.

5. *Succinyl-CoA conversion*: Succinyl-CoA is converted into succinate.

6. *Succinate oxidation*: Succinate is oxidized to form fumarate.

7. *Fumarate hydration*: Fumarate is hydrated to form malate.

8. *Malate oxidation*: Malate is oxidized to form oxaloacetate, which is then ready to start the cycle again.


Importance of the Krebs Cycle:

1. *Energy production*: The Krebs cycle produces NADH and FADH2, which are used to generate ATP in the electron transport chain.

2. *Cellular respiration*: The Krebs cycle is a critical step in cellular respiration, which is the process by which cells generate energy from glucose.

3. *Amino acid synthesis*: The Krebs cycle provides intermediates for the synthesis of amino acids, such as glutamate and aspartate.


Regulation of the Krebs Cycle:

1. *Feedback inhibition*: The Krebs cycle is regulated by feedback inhibition, where high levels of ATP and NADH inhibit key enzymes in the cycle.

2. *Allosteric regulation*: Key enzymes in the Krebs cycle are also regulated by allosteric interactions, where binding of regulatory molecules affects enzyme Activity 


"This Content Sponsored by Buymote Shopping app


BuyMote E-Shopping Application is One of the Online Shopping App


Now Available on Play Store & App Store (Buymote E-Shopping)


Click Below Link and Install Application: https://buymote.shop/links/0f5993744a9213079a6b53e8


Sponsor Content: #buymote #buymoteeshopping #buymoteonline #buymoteshopping #buymoteapplication"

Comments

Post a Comment

Popular posts from this blog

Understanding Amphibolic Pathways: Key to Energy Homeostasis and Cellular Metabolism in Health and Disease with Insights and Implications

 Amphibolic Pathway An amphibolic pathway is a metabolic pathway that plays a crucial role in energy production and utilization within cells. These pathways are unique in that they involve both catabolic and anabolic processes, allowing cells to efficiently manage energy resources. Key Characteristics 1. *Dual function*: Amphibolic pathways can be involved in both energy production (catabolism) and energy utilization (anabolism). This dual function allows cells to adapt to changing energy demands. 2. *Shared intermediates*: These pathways often share common intermediates between catabolic and anabolic processes. This sharing of intermediates enables cells to efficiently utilize energy resources. 3. *Regulation*: Amphibolic pathways are tightly regulated to ensure that energy production and utilization are balanced. This regulation is critical for maintaining energy homeostasis within cells. Examples 1. *Citric acid cycle (Krebs cycle)*: This pathway is a key example of an amphiboli...
Post a Comment
Read more

Exploring Kingdom Protista: Characteristics, Classification, and Diversity of Eukaryotic Organisms with Unique Cellular Structures and Functions

1. KINGDOM PROTISTA All single-celled eukaryotes are placed under Protista, but the boundaries of this kingdom are not well defined. What may be ‘a photosynthetic protistan’ to one biologist may be ‘a plant’ to another. In this book we include Chrysophytes, Dinoflagellates, Euglenoids, Slime moulds and Protozoans under Protista. Members of Protista are primarily aquatic. This kingdom forms a link with the others dealing with plants, animals and fungi. Being eukaryotes, the protistan cell body contains a well defined nucleus and other membrane-bound organelles. Some have flagella or cilia. Protists reproduce asexually and sexually by a process involving cell fusion and zygote formation. 1.1 Chrysophytes This group includes diatoms and golden algae (desmids). They are found in fresh water as well as in marine environments. They are microscopic and float passively in water currents (plankton). Most of them are photosynthetic. In diatoms the cell walls form two thin overlapping shells, whi...
Post a Comment
Read more